Is CBD Safe? An In-Depth Look at CBD's Effects, Interactions, and Risks

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The Key Points:

  • CBD is generally well-tolerated and has a good safety profile according to the World Health Organization.
  • There are potential interactions between CBD and certain medications like acid blockers, anticoagulants, pain relievers, and neuroleptics.
  • Use of CBD during pregnancy and breastfeeding is not recommended due to insufficient research.
  • While CBD is non-psychoactive and does not negatively impact memory, smoking CBD could have adverse effects on the lungs.
  • Mixing CBD and alcohol could potentially amplify alcohol's effects, and more research is needed to fully understand this interaction.

CBD is increasingly becoming a popular natural remedy for various health conditions. However, as popularity grows, so do the number of questions about its safety: Can CBD be dangerous? What does the World Health Organization say about it?

What the World Health Organization Says About CBD

In May 2018, the Expert Committee on Drug Dependence (ECDD) of the World Health Organization (WHO) released a report on the safety and effectiveness of CBD. In this report, the ECDD concluded that

"CBD is generally well tolerated and has a good safety profile."

However, the ECDD also noted that it is a "novel food," meaning that it doesn't have a long history of safe use. You should keep this in mind if you're considering taking CBD, especially if you're on other medications. While CBD is generally considered safe, you should always talk to your doctor before starting any new dietary supplement.

The ECDD affirmed in another article that it's unlikely that CBD could cause dependence or be abused. There are no human studies on the mental or physical dependence on CBD, but since the substance does not induce a high or any strong sensations, it's highly unlikely that dependence would develop.

CBD and Interactions with Medications

Taking CBD along with medications can be dangerous.

CBD oil can alter the functioning of enzymes in the body. This can cause some medications to work differently than they should. It has been proven that CBD oil can affect the action of these medications, for example:

  • Pantoprazole and Omeprazole (acid inhibitors)
  • Marcumar and Warfarin (anticoagulants)
  • Diclofenac (analgesic)
  • Risperidone, Haloperidol, Clobazam (neuroleptics)

However, interactions with other drugs metabolized by the enzymes CYP3A4 and CYP2D6 are also possible. These include calcium antagonists and beta blockers used for high blood pressure or heart diseases, antihistamines, antiretroviral drugs, immunosuppressants, and tricyclic antidepressants.

CBD during Pregnancy and Breastfeeding

There is not enough research on the safety of CBD during pregnancy and breastfeeding. Until more research results are available, it's best to avoid taking CBD during pregnancy or breastfeeding.

Does CBD Have Negative Effects on the Brain?

Ever since research into cannabis became possible in some countries, more and more substances from the cannabis plant are being discovered apart from the well-known THC, which has a intoxicating effect. Unlike THC, cannabidiol does not have psychoactive properties. It has been shown that CBD consumption does not negatively affect memory, in fact, the opposite might be true.

Is a Certificate of Analysis Enough to Ensure a CBD Product is Safe?

Some CBD product manufacturers provide certificates of analysis on their websites. These certificates verify the presence of CBD and the absence of THC.

At Nordic Oil, we ensure the quality of our products by regularly testing them. We maintain long-term relationships with the farmers from whom we source our cannabis to ensure that all plants consistently meet safety and legal requirements. Our dedicated quality assurance team also ensures that we adhere to all safety-related regulations.

Is Smoking CBD Dangerous?

Smoking is never healthy - Remember that cigarettes are a high risk factor for cancer, heart problems, and respiratory diseases. While CBD itself is proven not to be harmful, studies have shown that smoking can have long-term effects on the lungs.

Vaping CBD may be a healthier alternative to smoking and is an option if you're already using e-liquid.

Is It Dangerous to Mix CBD and Alcohol?

Some people believe that combining CBD and alcohol can have positive effects, such as reducing anxiety and promoting relaxation. However, there is little scientific evidence to support these claims. In fact, there is some evidence that CBD may enhance the effects of alcohol.

In a study, it was found that participants who took CBD before consuming alcohol experienced greater impairment than those who did not take CBD. The study was small-scale, and more research is needed to evaluate the potential risks and benefits of mixing CBD and alcohol.

Therefore, the answer to this question is: Yes, it could be dangerous to mix CBD and alcohol.

Is it Possible to Overdose on CBD?

So far, no study has reported an overdose of CBD oil. However, it's possible to take too much, with "too much" varying from person to person.

Is CBD Dangerous for the Liver?

Studies on this subject have mixed results. Most studies and clinical trials suggest that CBD can have positive effects on the liver. However, some rat studies concluded that excessive intake of CBD can lead to liver damage.


In conclusion, it's important to mention that CBD itself is not dangerous. It's well tolerated by humans and doesn't cause any psychotropic effect. Nevertheless, CBD can interact with medications and alcohol, which can potentially become dangerous. Always talk to your doctor before taking CBD in combination with medications.

Moreover, CBD is not recommended for pregnant and breastfeeding women, as there's not enough knowledge about its effects on embryos and infants.

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