CBD and Lansoprazole (e.g. Prevacid, Lanzor, Lansoprazol-ratiopharm)

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Understanding CBD and Lansoprazole

Before delving into the potential interactions between CBD (cannabidiol) and Lansoprazole, it's important to understand what these substances are and how they work in the body.

What is CBD?

CBD is a natural compound found in the Cannabis sativa plant. Unlike THC, another major component of cannabis, CBD does not produce a "high" or any form of intoxication. It has been recognized for its potential therapeutic properties, including anti-inflammatory, analgesic, and anti-anxiety effects.

What is Lansoprazole?

Lansoprazole, on the other hand, is a type of medication known as a proton pump inhibitor (PPI). It's commonly used to treat conditions caused by excess stomach acid, such as gastroesophageal reflux disease (GERD) and stomach ulcers. The drug works by reducing the amount of acid your stomach makes.

Internationally, Lansoprazole is sold under various brand names including Prevacid (in the USA and Canada), Lanzor (in France), and Lansoprazol-ratiopharm (in Germany).

Potential Interactions Between CBD and Lansoprazole

While CBD is generally well tolerated, it can interact with certain medications, potentially affecting how they are metabolized in the body. This is because CBD is processed by a group of enzymes known as cytochrome P450 (CYP450), which are also responsible for metabolizing many other drugs, including Lansoprazole.

By inhibiting the CYP450 enzymes, CBD could potentially increase the concentration of Lansoprazole in the body, leading to a higher risk of side effects. These side effects could include headache, nausea, diarrhea, abdominal pain, fatigue, and dizziness.

However, it's important to note that not everyone will experience these interactions or side effects. The effects can vary greatly depending on individual factors such as your overall health, the dosage of CBD and Lansoprazole you're taking, and whether you're taking any other medications.

Consulting with a Healthcare Professional

Given the potential for interaction, it's crucial to consult with a healthcare professional before starting CBD if you're currently taking Lansoprazole or any other medication. Your doctor can help you understand the potential risks and benefits, and can monitor you for any adverse effects.

It's also important to buy CBD products from reputable sources to ensure they are safe, and contain the advertised levels of CBD. Mislabeling and contamination are common issues in the CBD industry.


To sum up, while CBD has potential therapeutic benefits, it can interact with certain medications, including Lansoprazole. This interaction could potentially lead to increased side effects. Therefore, it's important to consult with a healthcare professional before starting CBD if you're currently taking Lansoprazole or any other medication.

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