CBD and Insulin Glargine (e.g. Lantus, Optisulin)

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Understanding CBD and Insulin Glargine

As more people turn to alternative therapies for various health conditions, there's a growing interest in the potential benefits and risks of cannabidiol (CBD). This article will focus on the interaction between CBD and a common medication for diabetes, Insulin Glargine, known under various brand names such as Lantus and Optisulin.

What is CBD?

CBD is a naturally occurring compound found in the Cannabis Sativa plant. Unlike its cousin, delta-9-tetrahydrocannabinol (THC), which is the major active ingredient in marijuana, CBD is not psychoactive. This means it does not cause a 'high' or change a person's state of mind, but it does appear to have numerous health benefits.

CBD works by interacting with the body's endocannabinoid system (ECS), a complex cell-signaling system that plays a key role in regulating a wide range of functions and processes including sleep, mood, appetite, memory, reproduction, and pain sensation.

About Insulin Glargine

Insulin Glargine, sold under the brand names Lantus and Optisulin among others, is a long-acting insulin used to treat both type 1 and type 2 diabetes. It works by helping your body use sugar properly, lowering the amount of glucose in the blood, and reducing the complications of high sugar levels such as kidney damage, nerve problems, and blindness.

Interactions between CBD and Insulin Glargine

At present, there is limited research about the specific interactions between CBD and Insulin Glargine. However, CBD is known to interact with certain enzymes in the liver responsible for metabolizing many drugs, including some types of insulin. This could potentially affect how Insulin Glargine is processed in the body and alter its effects.

Additionally, CBD may have an indirect impact on diabetes medications by influencing weight and insulin sensitivity. Some studies suggest CBD may help reduce body weight and increase metabolism, which could potentially improve insulin sensitivity and enhance the effectiveness of Insulin Glargine.

Important Considerations

  • Always consult your healthcare provider before starting any new supplement or medication, including CBD.
  • Monitor your blood sugar levels closely if you decide to use CBD, as it may affect how your body responds to Insulin Glargine.
  • Be aware that CBD products are not regulated by the FDA and their quality can vary significantly.


While there is promising research about the potential benefits of CBD, its interaction with Insulin Glargine is not fully understood. It's crucial to consult with a healthcare provider before starting CBD, particularly if you are taking medications like Insulin Glargine. As with any new supplement or medication, it's important to monitor your body's response and communicate any changes to your healthcare provider.

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