CBD and beta blockers (e.g. Concor, Bisoprolol, Atenolol, Tenormin)

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Understanding CBD and Beta Blockers

For many, Cannabidiol (CBD) has become a go-to remedy for various health issues such as anxiety, pain, and sleep problems. Yet, as with any supplement, it's essential to understand how it interacts with other medications. This article focuses on the potential interactions between CBD and beta blockers, such as Concor (Bisoprolol), Atenolol, and Tenormin.

What Are Beta Blockers?

Beta blockers, or beta-adrenergic blocking agents, are a class of drugs primarily used to manage abnormal heart rhythms, and to protect the heart from a second heart attack after a first one has occurred. They work by blocking the effects of the hormone epinephrine, also known as adrenaline. Here are some of the most common beta blockers:

  • Concor: Known as Bisoprolol in the medical community, this is a popular beta blocker used worldwide.
  • Atenolol: Marketed under the brand name Tenormin, Atenolol is another widely prescribed beta blocker.

How Does CBD Work in the Body?

CBD is one of many compounds, known as cannabinoids, in the cannabis plant. It works by interacting with the body's endocannabinoid system (ECS), a complex cell-signaling system that plays a role in regulating a range of functions and processes, including sleep, mood, appetite, and memory. Unlike its cousin THC, CBD does not have psychoactive effects, meaning it does not produce a "high".

Interactions Between CBD and Beta Blockers

Research on the interactions between CBD and beta blockers is still in its early stages. However, some studies suggest that CBD can interact with enzymes in the liver responsible for metabolizing many medications, including beta blockers. This interaction can potentially alter how these medications work, leading to an increase or decrease in their effects.

Specifically, CBD can inhibit an enzyme called CYP2D6, which is involved in metabolizing many drugs, including beta blockers. This inhibition can lead to higher levels of the medication in the bloodstream, increasing the risk of side effects.

Precautions and Consultations

Before starting CBD, it's crucial to consult with a healthcare provider, especially if you're on medications like beta blockers. They can provide guidance based on your current health status and medication regimen.

Remember, while CBD is generally well-tolerated, it can cause side effects in some people, including fatigue, diarrhea, and changes in appetite and weight. It's also worth noting that the FDA does not regulate the safety and purity of CBD products, so you can't always be sure of what you're getting.


While CBD has gained popularity for its potential health benefits, it's crucial to understand how it interacts with other medications, including beta blockers. Early research suggests that CBD can interfere with the metabolism of these drugs, potentially leading to increased side effects. As always, it's best to consult with a healthcare provider before starting CBD, especially if you're on other medications.

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